Take the extended-release tablet once daily with your evening meal. Take metformin and pioglitazone with meals. Related/similar drugs metformin, Trulicity, Lantus, Victoza, Tresiba, Levemir How should I take metformin and pioglitazone?įollow all directions on your prescription label and read all medication guides or instruction sheets. Metformin and pioglitazone is not approved for use by anyone younger than 18 years old. It may not be safe to breastfeed while using this medicine. Talk with your doctor about ways to keep your bones healthy. Women may be more likely to have a broken bone while using metformin and pioglitazone. Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. Talk to your doctor about the risks and benefits of this medicine.įollow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Metformin and pioglitazone may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Talk with your doctor about your specific risk. This medication may increase your risk of developing bladder cancer. Be sure your caregivers know ahead of time that you are using this medicine.Ĭongestive heart failure or other heart problems If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking metformin and pioglitazone. Metabolic acidosis or ketoacidosis (call your doctor for treatment). You should not use this medicine if you are allergic to metformin or pioglitazone, or if you have:
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